Agent Sandbox (port 9061)

This page demonstrates an experimental AI Agent interacting with a symbolic expert system implemented in Prolog.

This page is not a medical user interface and is not intended for clinicians to enter symptoms. The real expert system and its UI are located at: http://64.225.98.129:9060/

Reading the documentation and exploring the UI at port 9060 is recommended before using this sandbox.

Relationship between the two ports

Port 9060 — Expert System UI

Port 9060 hosts the real expert system. The system is implemented entirely in Prolog.

• a questionnaire interface for phenotype selection
• a knowledge base of rare diseases
• a phenotype database
• a symbolic reasoning engine implemented in Prolog

Disease descriptions can be explored here: http://64.225.98.129:9060/review

Port 9061 — Agent Sandbox

The current page (port 9061) is only a sandbox demonstrating how an AI agent could interact with the expert system.

This sandbox does not contain the expert system.

Instead, it simulates how external software (for example a hospital application) might send a clinical note to an agent that interacts with the expert system.

Architecture demonstrated in this sandbox

Clinical note
(simulated hospital software)

        ↓

Agent (port 9061)
phenotype normalization

        ↓

MCP request
task: diagnose

        ↓

Prolog reasoning engine
(port 9060)

        ↓

Candidate rare diseases

The phenotype normalization problem

Phenotype normalization is one of the major challenges in medical informatics.

Hospitals typically rely on standardized terminology systems such as:

• SNOMED CT
• Human Phenotype Ontology (HPO)
• ICD-10

Mapping clinical text to standardized phenotypes is a complex task and cannot be fully solved in a small demonstration system.

Machine-readable output

The agent returns a structured JSON output intended for software systems.

{
  "phenotypes": [
    "Myopia",
    "Hyperventilation"
  ],
  "candidate_diseases": [
    "biotinidase_deficiency",
    "fructose_1_6_bisphosphatase_deficiency",
    "holocarboxylase_synthetase_deficiency",
    "retinal_ciliopathy_due_to_mutation_in_usher_gene"
  ]
}

Test the agent

The form below simulates a clinical note sent by external software. For example, entering "Patient reports difficulty seeing distant objects and fast breathing" will generate the machine-readable output shown above.